Single-cell Atlas in Liver Cancer (scAtlasLC)

References

Ma L, Wang L, et al., Single-cell atlas of tumor cell evolution in response to therapy in hepatocellular carcinoma and intrahepatic cholangiocarcinoma. Journal of Hepatology. 2021 Jun 30. doi: 10.1016/j.jhep.2021.06.028. PMID: 34216724.
Ma L, Hernandez MO, et al., Tumor Cell Biodiversity Drives Microenvironmental Reprogramming in Liver Cancer. Cancer Cell 36(4): 418-430.e6. 2019. doi: 10.1016/j.ccell.2019.08.007. PMID: 31588021.
Ma L, Khatib S, Craig AJ and Wang XW, Toward a Liver Cell Atlas: Understanding Liver Biology in Health and Disease at Single-Cell Resolution. Seminars in Liver Disease. 2021. doi: 10.1055/s-0041-1729970. PMID: 34130336.
Heinrich S, Craig AJ, Ma L, Heinrich B, Greten TF, Wang XW, Understanding tumor cell heterogeneity and its implication for immunotherapy in liver cancer by single cell analysis. Journal of Hepatology 74(3): 700-715. 2021. doi: 10.1016/j.jhep.2020.11.036. PMID: 33271159.
Ma L, Heinrich S, et al., Multiregional single-cell dissection of tumor and immune cells reveals stable lock-and-key features in liver cancer. Nature Communications, 13(1), 7533. doi: 10.1038/s41467-022-35291-5. PMID: 36476645
Revsine M, et al., Lineage and ecology define liver tumor evolution in response to treatment. In revision.

scAtlasLC is developed by Lichun Ma at Liver Cancer Program.

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Each single-cell dataset was normalized independently. Gene expression levels may not be comparable between datasets. Illustrations were created using BioRender.

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